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Who Actually Invented Ibuprofen?

Get to know the real inventor of Ibuprofen, the pain reliever used by millions every day!

Who Actually Invented Ibuprofen?

Who Invented Ibuprofen?

Overview of Ibuprofen

Ibuprofen is an NSAID that is widely used for treating pain, fever, and inflammation. It is available in various forms, including tablets, capsules, and liquids, and is considered an effective alternative to opioid painkillers. The drug is known for its ability to reduce pain and swelling while being gentle on the stomach. It has a long history of safe and effective use and is one of the most commonly used drugs in the world.

Discovery of Ibuprofen

The discovery of ibuprofen can be traced back to the 1950s when a team of researchers at the Boots Pure Drug Company in England was working on developing a new class of painkillers. The team, headed by pharmacologist Stewart Adams, was focused on finding a compound that could reduce inflammation and relieve pain without causing any significant side effects.After screening hundreds of compounds, Adams and his team finally discovered ibuprofen in 1961. The compound was found to be effective in relieving pain and inflammation, and it showed minimal side effects. The researchers knew that they had a breakthrough on their hands and proceeded to develop the drug further.

Development of Ibuprofen

After discovering ibuprofen, Adams and his team spent the next several years working on refining the drug and testing its effectiveness and safety. They tested the drug on animals and human subjects, and the results were encouraging.In 1961, Adams and his team patented the drug and began marketing it as a prescription-only medication under the brand name Brufen. It quickly gained popularity, and by the 1970s, it had become the most prescribed drug in the UK. The drug was approved for use in the US in 1974, where it was marketed under the brand names Advil and Motrin.In 1983, ibuprofen became available over-the-counter for the first time in the US. This made it easier for people to access the drug and use it as a pain reliever. Today, ibuprofen is available in various forms and is sold under several brand names worldwide.


In conclusion, ibuprofen is a widely used drug that has revolutionized pain relief. Its discovery can be credited to the hard work and dedication of Stewart Adams and his team of researchers at the Boots Pure Drug Company. Their efforts have resulted in a drug that has improved the lives of millions of people around the world. Today, ibuprofen is one of the most widely used medications in the world, and its popularity is a testament to its effectiveness and safety.

Who Invented Ibuprofen?

Ibuprofen is a widely-used pain reliever, fever reducer, and anti-inflammatory medication that has been available in most parts of the world for decades. Although ibuprofen is a household name today, many people may not know who invented it and how it came to be one of the most popular over-the-counter medications in history. In this article, we will explore the history of ibuprofen and the people behind its discovery.

The History of Ibuprofen

Ibuprofen was first discovered by a research team led by Dr. Stewart Adams in the 1950s. Dr. Adams was a pharmacologist at Boots Pure Drug Company in Nottingham, England. At that time, many people were suffering from rheumatoid arthritis and other chronic painful conditions, but the available pain relief medications were either narcotic or had serious side effects.

Dr. Adams and his team set out to find a safe and effective alternative to the existing pain medications. They discovered that a chemical compound called 2-(4-isobutylphenyl) propionic acid, or ibuprofen, showed promise in reducing inflammation and pain in laboratory animals. Several years of testing followed before ibuprofen was ready to be marketed as a new drug.

In 1969, ibuprofen first became available in the UK as a prescription-only medication. A few years later, it was approved for over-the-counter sale in the United States and other countries. Since then, ibuprofen has become one of the most widely-used pain relievers in the world and is available in various forms, including tablets, capsules, syrups, and gels.

How Does Ibuprofen Work?

Mechanism of Action

Ibuprofen works by blocking the production of certain chemicals in the body that cause inflammation, pain, and fever. Specifically, it inhibits the activity of cyclooxygenase (COX) enzymes, which produce prostaglandins that play a key role in inflammation and pain.

Benefits of Ibuprofen

Ibuprofen is widely used to treat a variety of conditions, including headaches, menstrual cramps, arthritis, and sports injuries. It is also effective at reducing fever and inflammation.

Potential Side Effects of Ibuprofen

While ibuprofen is generally considered safe when used as directed, it can cause side effects in some people. Common side effects include stomach upset, headaches, dizziness, and rash. In rare cases, ibuprofen can cause more serious side effects such as liver damage, kidney damage, and bleeding in the stomach or intestines.


Dr. Stewart Adams and his team at Boots Pure Drug Company were instrumental in discovering and developing ibuprofen, which has become a household name and a trusted pain relief medication for millions of people worldwide. Ibuprofen's effectiveness in reducing inflammation, pain, and fever has made it a staple in medicine cabinets and first aid kits, but it is essential to use it responsibly and follow the recommended dosages to avoid potential side effects.

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